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Thursday, July 31, 2003

Salt controls size of DNA structures, could improve gene therapy

Researchers have found they can control the size of densely packed DNA structures by changing the salt concentration in solutions containing DNA. The finding could improve the efficiency of gene delivery for medical treatment and disease prevention.
Scientists are seeking to understand the natural mechanism of DNA condensation into nanostructures – in particular, toroids, which look like tightly wound garden hoses. Densely packed DNA is nature's efficient way of transporting genetic information, done particularly well by sperm cells and viruses.
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